Pueblo (I-25), CO

Store Information

2440 North Interstate 25
Pueblo, Colorado 81008

Phone: (719) 283-8017

Store Hours

Monday:8:00 AM - 10:45 PM
Tuesday:8:00 AM - 10:45 PM
Wednesday:8:00 AM - 10:45 PM
Thursday:8:00 AM - 10:45 PM
Friday:8:00 AM - 10:45 PM
Saturday:8:00 AM - 10:45 PM
Sunday:8:00 AM - 10:45 PM

#1 Pueblo, CO Dispensary

The Cannabis Depot is the premier provider of high-quality cannabis products in Pueblo, Colorado. Whether you’re exploring your options for the first time or an experienced cannabis enthusiast looking for just the right product to spice up your rotation, you can count on our experienced, knowledgeable team to help you find the best fit for any occasion.

From the moment you walk through the doors of our dispensary, you’ll know in an instant that you’ve come to the right place: a one-stop shop for all your cannabis needs. You’ll find a warm, comfortable atmosphere, an expertly curated selection of products, and prices that make your cannabis experience that much more enjoyable. 

Expert budtenders to help you find the best products.

Expert budtenders to help you find the best products.

Hundreds of products to choose from.

Hundreds of products to choose from.

Our Products 

When you visit The Cannabis Depot, you can shop with confidence. Every product in our inventory is lab-tested and quality-assured. While browsing our selection, you’ll find an impressive range of product types, everything from top-shelf flower and pre-rolls to a vast assortment of tinctures, vape pens, gummies, and topicals. They’re grown and produced by some of the most respected brands in the cannabis industry, companies just as committed as we are to consumer safety and your complete satisfaction.

Our Every Day Deals 

At The Cannabis Depot, the price you see is the price you pay. All applicable fees and taxes are calculated into your out-the-door (OTD) cost. With our competitive pricing structure and daily deals, experiencing the best of everything cannabis has to offer is a lot more affordable than you might expect.

Take the everyday price on our ground and mid-shelf flower, for example, products that sell for $29.00 and $49.00/OZ OTD. Our 1-gram pre-roll prices start at just $6. Once you’ve also factored the price of our 1-gram 1865 carts, select concentrates, and our current offering on CANNAMERICA gummies into the equation, it’s easy to see how you could explore multiple product types without breaking the bank.

Locations & Business Hours 

Our business hours are easy to remember because they’re the same every day, even on weekends and holidays. You can drop by between 8:00 a.m. and 10:45 p.m. Monday through Sunday, 365 days a year. It doesn’t get much easier than that.

Located on I-25 in Pueblo, CO

Located on I-25 in Pueblo, CO

The Brands We Carry 

Many people feel somewhat intimidated trying to navigate a wide selection of cannabis products, at least at first. But there are numerous advantages to having your pick of brands from our diverse menu. Whether you prefer smoking, vaping, topical application, or enjoying the flavor of a cannabis-infused confection, you’ll have plenty of THC levels, CBD concentrations, and terpene profiles to choose from.

In addition to our top-quality flowers and pre-rolls, you’ll find a varied selection of products from in-demand brands that our budtenders know they can recommend with confidence, including Incredible edibles, Green Dot Labs, Harmony Extracts, and Mary’s Medicinals.

Could The Cannabis Depot Be Your One-Stop Shop for Premium Cannabis? 

The Cannabis Depot Company is a leading retailer and distributor of premium cannabis. We’ve built that reputation on our commitment to providing an impressive selection of expertly curated, high-quality products, exceptional service, and a safe, comfortable shopping experience.

Whether you’re looking for a pre-roll that will leave you feeling energized and focused, a delicious cannabis-infused edible to help calm your mind, or a topical to ease muscle tension, visit our convenient location in Pueblo, Colorado. Our friendly, knowledgeable staff will help you find just the right fit for your needs, preferences, and lifestyle.


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Disclaimer: You must be at least 21 years of age to use this website and/or purchase products from The Cannabis Depot. By using this website, you represent and affirm that you are at least 21 years old. Any attempt to misrepresent your age will result in immediate termination of your access and potential legal consequences. Cannabis is regulated by both state and federal laws. The information and products on this website are intended solely for those who are in compliance with their local jurisdiction's legal regulations concerning the possession, use, and sale of cannabis. The content on this website is for informational purposes only and should not be considered medical or legal advice. Always consult with a qualified professional before making any decisions related to cannabis. Cannabis is a psychoactive substance, and its effects can vary from person to person. If you decide to consume cannabis products, do so responsibly and be aware of your limits. Cannabis Products are not intended to diagnose, treat, cure or prevent any disease. Results from these products may vary. These items are not intended to cure, treat or prevent any diseases. The products listed on this website have not been approved by the FDA and are not intended to diagnose, treat or cure any disease or ailment. Always check with a physician before trying any new dietary supplement or medicinal herb. While we strive to provide accurate and up-to-date information, The Cannabis Depot makes no warranties or representations regarding the completeness, accuracy, or timeliness of any information on this website.

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